The north terminus of Nassau St. North is Roslyn Crescent and travels in a southeast direction, crossing Pembina Highway, swinging southwest before joining up with Garwood Avenue.

Its route length is 1.3 km (0.81 mi) The north terminus of Nassau St. South is Brandon Avenue and travels in a southeast direction ending near Churchill Drive with a break near Kylemore Avenue.

55 Nassau, a 38-floor condominium in the Fort Rouge area, is currently the 5th-tallest building in Winnipeg and the tallest residential building in the city (until the completion of the Artis Reit Residential Tower on 300 Main Street).

[2] At the time of its opening in 1970, it was the tallest apartment building in western Canada, standing at 109 metres (358 ft) tall.

[3][2] 738 Nassau is a multifamily housing complex designed by Manitoba architect Gustavo da Roza.