[2] The idea to fuse the two genres was proposed by Dan Sanchez who wrote Natanael's first corrido tumbado, "Soy el Diablo".

[4] When he first taught himself to play the piano at thirteen, he learned Mexican band Maná's "Rayando el Sol" off of YouTube.

[4] In 2019, he eventually signed to the independent label Five Music, where he released his debut single "El de los Lentes Gucci".

[11] He would eventually collaborate with Puerto Rican rapper Bad Bunny on the remix for "Soy el Diablo", which was the second single from his debut album Todo Es Diferente.

[16] Cano was the first musician to fuse this variant of the two genres together which has made him stand out, which has led him to be the first Mexican to be recognized as the artist of the month through Apple Music Up Next, "a show aimed at discovering rising stars that in previous years advanced several of today's top talents".

[17] Cano is best known for his creation of corridos tumbados which are inspired in the traditional songs of Mexico and combine the lyrics of trap music and sometimes hip-hop.

On 20 August 2024, Cano was arrested in Hermosillo for bribery; a video in which he appeared to give money to a police officer had spread on social media in March.