"Nathalie's" was located in the back of an antique shop owned by her husband in Social Circle, Georgia.
From 1975 Dupree became the director of a cooking school at Rich's department store in Atlanta, instructing over 10,000 students over a decade of teaching.
[3][4][5] Guests and teachers at the school included Shirley Corriher, Paula Wolfert, Julia Child, Paul Prudhomme and Jacques Pepin.
The show and a companion cookbook brought Dupree to regional and national prominence, establishing her as an influential culinary figure.
[2] Dupree was the author of 15 cookbooks, selling nearly a million copies, and the host of more than 300 national and international cooking shows, which have aired since 1986 on PBS, The Food Network, and The Learning Channel.
[3][4] She was a founder and two-time president of the International Association of Culinary Professionals, founder and co-president of both the Atlanta and Charleston, South Chapters of Les Dames d' Escoffier, founding chairman of the Charleston Food and Wine Festival, and past president of the Atlanta Chapter of the International Woman's Forum.
She expressed a willingness to work alongside fellow South Carolina Senator Lindsey Graham to "bring home the bacon" for the state.