Previously she was director of the École nationale d'administration (ENA) from 2012 to 2017 and served as the French Minister for European Affairs from 21 June 2017 to 27 March 2019.

[4] On 21 June 2017, Loiseau succeeded Marielle de Sarnez as the French Minister for European Affairs.

[15] She was selected by the European Union as the chief of mission of its observation team to monitor the 2025 Kosovan parliamentary election.

[16] In a 2022 letter to European Commissioner for the Environment, Oceans and Fisheries Virginijus Sinkevičius, Loiseau – together with Pierre Karleskind and Stéphanie Yon-Courtin – urged the EU to take measures to end British water treatment facilities’ discharges of raw sewage into shared waters, part of what they argued was an unacceptable lowering of environmental standards since Brexit.

[17] Also in 2022, Loiseau and Bart Groothuis wrote a letter to local officials in Strasbourg, criticizing a deal between Chinese technology company Nuctech and Strasbourg Airport to provide airport scanning systems, arguing the firm would get access to data on its travelers, including EU lawmakers.

"[20] The quote was reprinted by Le Journal du Dimanche,[21] and in response to the widespread international media coverage Loiseau clarified that she does not own a cat, and her comments were intended as a joke.