Nathaniel Wales was an American businessman and politician from the Commonwealth of Massachusetts.

He worked as a teacher in the Brockton area and was a high school principal in Pawtucket, Rhode Island, until 1843, when he entered the retail business in Stoughton, Massachusetts.

[3] In 1862, Massachusetts Governor Andrew appointed Wales commissioner to superintend the drafting of militia for Norfolk County.

Afterwards Wales was appointed by President Lincoln as United States commissioner of the Board of Enrollment for the Second District of Massachusetts from 1863 to 1865.

[4] In 1867, Wales was appointed assessor of the second district of internal revenue and held it until it was abolished in 1872.