It works to reduce HIV-related morbidity and mortality through strategic planning, policy formulation, advocacy, research, and effective implementation of interventions across the country.

Its purpose is to coordinate and control HIV/AIDS prevention, treatment, and care across Nigeria.

[3] NACA's jurisdiction encompasses the entire country, overseeing HIV/AIDS prevention, treatment, and care initiatives across all states and regions.

[4] The agency collaborates with several local and international bodies in its efforts to combat HIV/AIDS in Nigeria.

Additionally, NACA works with NGOs, civil society organizations, and global health funding agencies to implement HIV/AIDS programs and policies across the country.