National Highway 28 links the industrial town of Barauni in Bihar with the capital city of Uttar Pradesh, Lucknow, via Gorakhpur.

It spans across the districts of Begusarai, Samastipur, Muzaffarpur, East Champaran and Gopalganj in Bihar and Kushinagar, Deoria, Gorakhpur, Sant Kabir Nagar, Basti, Ayodhya, Barabanki and Lucknow in Uttar Pradesh and touches some major cities and towns on the way.

National Highway 28 starts at the junction with National Highway 31 near Barauni and passes north-west through DalsinghSarai, Samastipur, Muzaffarpur, Motipur, Mehsi and Chakia, turns westwards at Piprakothi about 10 km (6.2 mi) before Motihari, again becomes north-west bound near Gopalganj and leaves the state past Kuchai Kot to enter Uttar Pradesh.

Although well maintained otherwise, NH 28 has bad strip of 40 km (exact) in between Saryu river bridge and UP-Bihar border (near Gopalganj, Bihar).

[1] Lauria Areraj, the historic town of Ayodhya and Tanda and Rajesultanpur - renowned for its handloomed cotton cloth industry - are some tourist places situated near the National Highway 28, at various points on the way.