The National Institute of Astrophysics, Optics and Electronics (in Spanish: Instituto Nacional de Astrofísica, Óptica y Electrónica, INAOE) is a Mexican science research institute located in Tonantzintla, Puebla.

Founded by presidential decree on November 12, 1971, it has over 100 researchers in Astrophysics, Optics, Electronics and Computing Science, with postgraduate programs in these areas.

INAOE is one of 30 public research centers sponsored by the National Council of Science and Technology of Mexico (CONACyT).

The Institute, in partnership with the University of Massachusetts Amherst, developed the Large Millimeter Telescope / Gran Telescopio Milimétrico on the Puebla-Veracruz border.

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