Born in Corinth, Mississippi, Biggers received a Bachelor of Arts degree from Millsaps College in 1956 and was in the United States Navy from 1956 to 1960, achieving the rank of Lieutenant.

He received a Juris Doctor from the University of Mississippi School of Law in 1963.

[1] On March 1, 1984, Biggers was nominated by President Ronald Reagan to a seat on the United States District Court for the Northern District of Mississippi vacated by Judge William Colbert Keady.

His service was terminated on October 15, 2023, due to death.

[1] Neal Brooks Biggers Jr. died in Oxford, Mississippi on October 15, 2023, at the age of 88.