The northern segment begins at Nebraska Highway 4 east of Plymouth and ends at Interstate 80 north of Pleasant Dale.

The southern branch of Nebraska Highway 103 begins at an intersection with NE 8 south of Diller.

It heads in a northerly direction through farmland, turning briefly to the northwest as it passes through De Witt.

The highway continues heading north and slightly to the northwest until it meets NE 33 in Crete.

Also during this timeframe, N-103 was rerouted to the west and extended north through Crete, Pleasant Dale and terminated at a newly constructed interchange with I-80.