Neckar-Odenwald-Kreis is a Landkreis (district) in the north of Baden-Württemberg, Germany.

Neighboring districts are (from east clockwise) Main-Tauber-Kreis, Hohenlohe-Kreis, Heilbronn, Rhein-Neckar-Kreis, Odenwaldkreis (Hesse) and Landkreis Miltenberg (Bavaria).

The district's coat of arms might be described thus: Per pale dexter bendy lozengy argent and azure, sinister gules a wheel spoked of six argent.

The coat of arms shows the symbols of the two historical rulers of the district.

On the dexter (armsbearer’s right, viewer’s left) side is the blue and white "bendy lozengy" (that is, slanted diamond shapes) of the Wittelsbach family as owners of the Electorate of the Palatinate; on the sinister (armsbearer’s left, viewer’s right) side is the Wheel of Mainz, a symbol of the old Electorate of Mainz.