[1] It is a simple wire-frame, two dimensional drawing of a cube with no visual cues as to its orientation, so it can be interpreted to have either the lower-left or the upper-right square as its front side.
[6] The phenomenon has served as evidence of the human brain being a neural network with two distinct equally possible interchangeable stable states.
[8][2] During the 1970s, undergraduates in the Psychology Department of City University, London, were provided with assignments to measure their Introversion-Extroversion orientations by the time it took for them to switch between the Front and Back perceptions of the Necker Cube.
[11] The Necker cube is used to illustrate how vampires in Peter Watts' science fiction novels Blindsight (2006) and Echopraxia (2014) have superior pattern recognition skills.
One of the pieces of evidence is that vampires can see both interpretations of the Necker Cube simultaneously, which sets them apart from baseline humanity.