The Neil House was a historic hotel on High Street in Downtown Columbus, Ohio.

It was made of brick and black walnut, all taken from William Neil's farm in Wyandot County, Ohio.

William Neil built the hotels after arriving in the city in 1818, and having operated a tavern in the location from 1822 to 1839.

[1] Neil and his wife Hannah also became known for his stagecoach company, her mission for orphaned children, and their farm that became the Ohio State University campus around 1870.

This third hotel opened in August 1925, in a celebration that included a dinner and dance for 770 investors and leading residents.