Sperry was born and raised in College Station, Texas[1] where he graduated A&M Consolidated High School as Salutatorian and Student Body President.
[citation needed] From 1970 to 1977, he worked as a Horticulture Specialist for the Texas Cooperative Extension.
[citation needed] Neil Sperry hosted a radio show on Dallas station KRLD 1080-AM for over thirty years.
On his February 13, 2010 broadcast, Sperry informed his audience that KRLD was exercising a 180-day opt-out clause in their contract.
His Complete Guide to Texas Gardening (published 1982 with a second edition in 1991), has been popularly known as the "boot book," in reference to its cover art.