[4] With an early interest in neuroscience,[4] he graduated from St. Gregory's College and received his medical degree from the University of Ibadan.
[5] As a Commonwealth Scholar, he then attended the University of London in the United Kingdom, where he later obtained an MSc in Occupational Medicine as well.
[4] He did his neurosurgical residency training and completed a Ph.D. in the neuroscience graduate program at Emory University[6][3] in Atlanta, Georgia.
[9] Oyesiku's current research includes the investigation of the development of pituitary adenomas using genome-wide association studies and whole genome sequencing methods.
[5] Currently, he is the chair of the department of Neurological Surgery and Professor of Medicine (Endocrinology) at the University of North Carolina in Chapel Hill.
[6] In 2001, Oyesiku and his team of researchers were responsible for performing the first studies on high throughput gene expression studies that identified unique aspects of pituitary adenoma gene expression which led to a new imaging procedure and potential targeted therapy of pituitary tumors.
[10] His laboratory contains one of the largest pituitary tumor banks connected to a clinical database to study natural history, treatment outcomes, and molecular correlations.