[1] It is operated by the Nemours Foundation, a non-profit organization created through the last will and testament of philanthropist Alfred I. du Pont by his widow Jessie Ball duPont in 1936, and dedicated to improving children's health.

"[15] As of December 2023, the duPont Charitable Trust's portfolio is worth almost $10 billion, which helps financially support Nemours Children's Health.

[17] The Ronald McDonald House of Delaware adjacent to the hospital provides sleep rooms and showers for the parents and families of children receiving treatment.

[20] In 2022, Nemours began a $40 million expansion in southeastern Pennsylvania in which the health system will open three new specialty care sites by the winter of 2024.

[24] The hospital offers a comprehensive range of pediatric specialties and advanced surgical procedures, including kidney and bone marrow transplants and heart reconstruction.

[27][28][29][30][31] In March 2023, Nemours expanded cancer and blood disease research following a $78 million grant from the Lisa Dean Moseley Foundation.