[2] Unique variants included the AN440LF-ETB trolleybuses produced for Massachusetts Bay Transportation Authority (MBTA), featuring a third passenger door on the street (driver's) side,[3] the DMA-460LF dual-mode buses for the Silver Line (MBTA) with trolley poles and a diesel engine, the AN440/3 3-axle variant with a dead third axle for Los Angeles County Metropolitan Transportation Authority (LACMTA), and the 1-foot (0.30 m) shortened AN460RC (aka AN459) built for New Jersey Transit (NJT).

Exterior roof and side wall panels are of double galvanized steel, sealed to the skeleton with a combination of spot welding and gluing.

[12][11]: 4-94 to 4-102 Neoplan USA was also offering the "Advanced Design" N412 bus to compete with the GM Rapid Transit Series and Flxible Metro.

[17] Pennsylvania won a commitment from Neoplan USA to build an assembly plant in the state as a condition to fulfill the order; Neoplan USA announced its intent to add a Pennsylvania factory in 1982[18] and revealed a scale model of the site chosen in Honey Brook in 1984,[19] but assembled all of the Pennliners in Lamar due to the delivery deadlines.

[21] Although the Honey Brook site assembled buses briefly in 1986, it would later become the headquarters of Neopart, Neoplan USA's part distribution operation.

[29] The PennDOT buses, nicknamed "Pennliners", also were prone to premature corrosion,[30] as experienced by the Port Authority of Allegheny County (PAT).

The bus networks that have or have had them in service include MBTA in Boston, SEPTA in Philadelphia, WMATA in Washington, D.C., ABQ RIDE in Albuquerque, New Mexico, and LACMTA in Los Angeles.

The 1982 contract was a pooled purchase from 16 different transit agencies, with the majority going to SEPTA in Philadelphia (450) and Port Authority of Allegheny County (PAT) in Pittsburgh (410).

AN440 and AN460 models were ordered by the San Francisco Municipal Railway (Muni) to replace their aging bus fleet and delivered starting in 2001, but they proved troublesome.

Among the problems were insufficient, excessively noisy cooling fans (sounds reached up to 90 dB), faulty transmissions, maintenance intensive brake systems (requiring service every 5,000 miles (8,000 km)), and cracking frames.

Bi-State Development Agency, dba Metro, has a small fleet of Neoplan Buses for its MetroBus service, and since March 30, 2009, has retired them.