On 15 November 1850, the station was opened for freight traffic by the Palatine Ludwig Railway (Pfälzische Ludwigsbahn).

[5] As early as 7 September 1850, the first coal train ran on the branch line from Heinitz via Neunkirchen.

A new marshalling yard was built in 1912 in the district originally called Schlawerie (now Sinnerthal).

The outbreak of war on 1 August 1914 delayed the construction of the station building considerably.

The building was completed only in 1923; it was regarded as the most beautiful station built by the Deutsche Reichsbahn railway division of the Saarland.

Also re-opened were the Neunkirchen–Homburg line (with Homburg Central Station still closed) and the Nahe Valley Railway from Neunkirchen to Bad Kreuznach.

[6] The station played a major role because of the heavy industrialisation of Neunkirchen with coal mines and the steel works.

On 13 May 1966, electric trains began running through Neunkirchen on the line from Wemmetsweiler to Homburg.