[2] The NBT toolbox provides unique features for analysis of resting-state EEG or MEG recordings.

For an adequate understanding of quantitative changes in neurophysiological signals, such as electroencephalography (EEG) or magnetoencephalography (MEG), as a consequence of disease, experimental manipulations, or genetic variability there is a need to apply multiple biomarker algorithms.

The development of the NBT toolbox was started in 2008 by Simon-Shlomo Poil and Klaus Linkenkaer-Hansen from the VU University Amsterdam, the Netherlands.

Later the developer team was joined by Rick Jansen, Richard Hardstone, Sonja Simpraga, and Giuseppina Schiavone.

[citation needed] The toolbox and its associated tutorial website has served as a major part of courses at the VU University Amsterdam; such as, the Human Neurophysiology course (with on average 100 students each year), and the advanced human neurophysiology.