Neurosecretion is the release of extracellular vesicles and particles from neurons, astrocytes, microglial and other cells of the central nervous system.
[1][2] In 1928, Ernst Scharrer hypothesized that neurosecretory neurons in the hypothalamus of teleost fish, Phoxinus laevis, had secretory activity similar to that of endocrine gland cells.
In simpler organisms neurosecretion mechanisms regulate the heart, the process of metamorphosis, and directly influences the development of the gonadal function.
Neurosecretory cells, found in clusters in the medial and lateral parts of the brain, control corpora allata activity by producing juvenile hormone during the larval or nymphal instars,[6] the phase between periods of molting in insects.
[5] Neurosecretion in Tasar Silkworm, Antheraea mylitta Drury was investigated by Tripathi, P N et al.,(1997)and they suggested the presence of multilobed corpora allata in this lepidopteran insect.