Neurosis and Human Growth: The Struggle Toward Self-Realization is the magnum opus of German-American psychoanalyst Karen Horney.

In Horney's view, the key difference between neurosis and healthy growth is the difference between compulsive actions fueled by anxiety and spontaneous actions fueled by one's full range of emotions.

Horney describes self-realization as the development of a person's given potentialities, and compares it with the process of an acorn growing, given fertile soil, into a tree.

The principal subject of the book, however, is what happens when a person's spontaneity is crushed in early life.

The person will slowly lose touch with that spontaneity or "real self" and develop, instead, a reactive self which is constructed to respond to dangers of various kinds (see True self and false self).