Nevoid melanomas are clinically significant because they are difficult to distinguish from a benign nevus of the skin, which requires no treatment and is common on most individuals.
Nevoid melanomas are difficult to identify because of their strong resemblance to benign nevi of the skin.
[2][3] Nevoid melanomas frequently present as isolated papules, nodules, or wart-like in appearance.
[4] High-powered imaging tools may identify one or more traits that prove a lesion is a malignant melanoma, rather than a benign nevus:[2] Additionally, dermatoscopy may reveal discoloration, border irregularities, and other patterns typical of other kinds of melanoma, but which are too small or subtle to be seen with the naked eye.
[3] Treatment of a nevoid melanoma typically focuses on surgical removal of the primary lesion.