Polypoid melanoma is a rare cutaneous condition, a virulent variant of nodular melanoma.

[1]: 696  Polypoid melanoma is a subtype of nodular melanoma, the most aggressive form of melanoma (a skin cancer).

[2] Polypoid melanoma is distinguished by a profile that resembles cauliflower and an uneven surface.

[3] Therapies for metastatic melanoma include the biological immunotherapy agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; and an MEK inhibitor trametinib.

[4]