Route 10 is a 144 kilometre long highway starting in Fredericton and ending in Sussex, New Brunswick, Canada.

The road goes northeast from the Fredericton suburb of Barker's Point to the village of Minto, then loops around Grand Lake through Chipman to Youngs Cove.

While passing through Minto, Route 10 forms Pleasant Drive, and in Chipman, it forms parts of Bridge Street and Main Street.

The original routing of Route 10 looped around Grand Lake from Sheffield through Minto, Chipman and Youngs Cove, then met the former main Fredericton-Moncton road (then known as Route 9) near Codys.

In the 1940s, a direct road was built from Minto to Fredericton, passing the site of the former World War II internment camp at Ripples.