It had branch lines to Kingston, Port Jervis, Monticello, Delhi, Utica and Rome, New York and Scranton, Pennsylvania.

[12] Access to New York City was provided by the Middletown, Unionville and Water Gap Railroad and the New Jersey Midland Railway beginning in 1872.

By acquisition of these assets and construction of a new line to Sylvan Beach on the east shore of Lake Oneida, the O&W extended its operations into new market areas, and the Sylvan Beach Loop became a seasonally-significant corridor by providing transportation to central New York's recreational resort area.

By 1889, the O&W added two new branches, New Berlin to Edmeston, and Port Jervis to Monticello, connecting to the main line at Summitville, New York.

[17] The last passenger train (from Roscoe, New York, just north of Livingston Manor, to Weehawken Terminal) operated on September 10, 1953.

[20] The bankruptcy court finally ordered complete abandonment, and the last freight train ran from Norwich to Middletown on March 29, 1957.

Three large scrap dealers bought the entire right-of-way from the bankruptcy court soon afterward, and removed nearly all of the rails and bridges in 1958 and 1959.

[20] Certain sections of track serving shippers, many of which were industrial factories, were transferred by the bankruptcy court to other railroads, allowing continued rail access to the plants.

[23] The Starlight station in Wayne County, Pennsylvania was acquired by Buckingham Township and servies as its Municipal Building.

On September 27, 1955, a 50-car O&W train in Hamilton, New York, traveling on a mainline approached a switch set for a siding which led to a coal trestle.

One of the freight cars involved in the accident was loaded with chocolate bars from the Nestlé plant in nearby Fulton, New York.