NY 157 is a two-lane, narrow, winding route that runs along an escarpment overlooking the Capital District.

NY 157 was assigned to its current alignment as part of the 1930 renumbering of state highways in New York.

At the junction with Singer Road, NY 157 turns southeast once again, crossing past similar surroundings.

[3] The direction changes again southward as NY 157 passes the campground for Thompson's Lake State Park.

Now running lakeside, the route turns southeast along the southern shore of Thompson's Lake, passing many waterside residences.

[3] After making a bend to the northeast, the route junctions with the eastern terminus of CR 256, where NY 157 turns eastward through Berne.