NY 406 continues northeastward through farmlands, intersecting with Quackenbush Road (CR 62) on its way into the town of Rotterdam, where the route passes to the south of Schenectady Memorial Park in the hamlet of Pine Grove.

[4] The origins of NY 406 date back to January 3, 1922, when the Schenectady County Board of Supervisors passed a resolution expressing the county's desire to have the state of New York reconstruct the road as a state highway.

At the same time, the board withdrew the county's support for a state project to rebuild part of what is now NY 147 in order to offset the mileage gained by adding Giffords Church Road to the state highway system.

The changes required the approval of the New York State Department of Highways,[5] which rejected the proposal by January 11.

[6] Despite this fact, Giffords Church Road was taken over by the state of New York by 1926[7] and designated NY 406 at some point between 1933 and 1936.