Nicks Creek is a 11.13 mi (17.91 km) long 3rd order tributary to Little River in Moore County, North Carolina.

According to the Geographic Names Information System, it has also been known historically as:[1] Nicks Creek rises on the Little River and Jackson Creek divide about 0.5 miles east of West End in Moore County, North Carolina.

Nicks Creek then flows easterly to meet the Little River about 1 mile east of Whispering Pines.

[2] Nicks Creek drains 56.99 square miles (147.6 km2) of area, receives about 49.3 in/year of precipitation, has a topographic wetness index of 437.66 and is about 46% forested.

[4] Nicks Creek is classed as WS-III in terms of water quality.