Nicholas Lopez (born March 13, 1995) is an American professional baseball shortstop and second baseman in the Chicago Cubs organization.

[4][5] Lopez made his professional debut with the Burlington Royals[6] and spent the whole 2016 season there, posting a .281 batting average with six home runs, 29 RBIs and 24 stolen bases in 62 games.

In 2017, he spent time with both the Wilmington Blue Rocks and the Northwest Arkansas Naturals, batting a combined .279 with two home runs, 38 RBIs, 24 stolen bases and a .704 OPS in 129 games.

Having hit .118 in 34 at-bats in Spring Training, Lopez was optioned to Triple-A Omaha, with Whit Merrifield expected to assume the starting second baseman role.

[24][25] In his first start for the Braves on August 12, Lopez recorded four hits, including a 3-run home run, at the plate and finished the game on the mound, pitching a scoreless ninth inning in a 21–3 victory against the New York Mets.

[26] On November 16, 2023, the Braves traded Lopez to the Chicago White Sox, along with Michael Soroka, Jared Shuster, Braden Shewmake, and Riley Gowens for Aaron Bummer.

On November 12, 2024, Lopez was removed from the 40–man roster and sent outright to the Triple–A Charlotte Knights, but he rejected the assignment and elected free agency.