Nicole Renee DeHuff (January 6, 1975 – February 16, 2005) was an American actress best known for her role in the comedy movie Meet the Parents (2000).

She began her acting career by earning a bachelor's degree in drama from Carnegie Mellon University in 1998.

[1] DeHuff also married executive producer and director Ari Palitz, whom she met at Carnegie Mellon.

[2] DeHuff landed her first big role in the hit movie comedy Meet the Parents, in which she played the character of Teri Polo's sister, Deborah Byrnes.

In the days preceding her death, DeHuff checked into two hospitals for respiratory problems, and was misdiagnosed both times as having bronchitis.