The Nikon F100 is a professional 35 mm film-based single-lens reflex camera body introduced in 1999.

The meter in the F100 uses a 10 segment light sensor and uses distance information from Nikon D-type and G-type lenses for more accurate exposure calculations when using direct flash.

Also incorporated into the camera is Nikon's Dynamic Autofocus system and a 4.5 frame per second motor drive with automatic rewind.

The top motor drive speed can be boosted to 5 frames per second with the addition of the Nikon MB-15 battery pack.

During its production run, Nikon replaced the film rewind spool for these cameras due to a manufacturing defect.