Niles is a census-designated place (CDP) in Ottawa County, Kansas, United States.

[2] A post office was opened in Niles (originally called Nilesville) in 1885, and remained in operation until it was discontinued in 1974.

[3] The 2020 United States census counted 56 people, 31 households, and 23 families in Niles.

22.6% of households consisted of individuals and 6.5% had someone living alone who was 65 years of age or older.

[12] The community is served by Solomon USD 393 public school district.