At age 39, Nina begins a nursing career in the Madeleine Brès Hospital's internal medicine department, headed by her ex-husband Dr. Costa Antonakis.
While taking care of her daughter Lily, who is suffering from cancer, she chooses to be a nurse, surreptitiously reviving Costa's war with his rival, Dr. Proust, and disturbing Costa's relationship with a young pediatrician.
The directors of the first season were Éric Le Roux and Nicolas Picard.
The second season was directed by Le Roux, Hervé Brami and Adeline Darraux.
Le Roux, Brami and Emmanuelle Dubergey also directed the third season.