As a protégé of the Angelina Marić Foundation, he attended doctoral studies in the field of private law in Paris from 1910 to 1912.
He left his career as a professor after Nikola Pašić formed the first homogeneous radical government on December 16, 1922, and appointed Ninko Perić as Minister of Social Policy.
The continuation of his career was inextricably linked with Nikola Pašić, King Alexander and Petar Živković, according to whose wishes he was given various functions.
After the Marseille assassination, he remained on good terms with Bogoljub Jevtić, who offered him the position of ambassador in Bucharest in January 1935.
Milan Stojadinović wanted to transfer him as an ambassador to Brussels in January 1936, but the Belgian government did not give his approval.
When Nikola Pašić approved Ninko Perić's transfer from the Ministry of Foreign Affairs to the University of Belgrade, he ordered his father-in-law Draža Petrović to start preparing the ground for his parliamentary candidacy in the Pocer region, judging that it would be better for him to stay in politics than to dedicate himself to an academic career.
As a representative of the Pocer region, Ninko Perić was responsible, among other things, for strengthening the party structure in Eastern Slavonia.
However, King Aleksandar and Petar Živković began to show more and more trust and affection towards Ninko Perić from 1925, and his career as a politician and as a civil servant continued to develop under their protection.
Their relationship cooled down suddenly, since Perić succeeded Stojadinović as the head of the Ministry of Finance in the government of Nikola Uzunović in April 1926.