181 Squadron RAF was a Royal Air Force Squadron formed as a fighter-bomber unit in World War II.

The squadron formed on 25 August 1942 at RAF Duxford and was supplied with Hurricane and Typhoon aircraft.

The squadron operated the Typhoons from several locations in the United Kingdom including RAF Appledram, RAF Snailwell, RAF Lasham, RAF Odiham and RAF Hurn.

The squadron attacked V-1 flying bomb launch sites and supported the Normandy landings in June 1944, then moved to France where it followed the Allied advance across Europe, seeking targets of opportunity.

The squadron disbanded at B 156/Lüneburg, Germany on 30 September 1945.