NHS serves students in grades 9 through 12, and graduated its first class in 1876.

[1] Noblesville is an original member of the Indiana High School Athletic Association, one of fifteen schools listed as charter members in the IHSAA Handbook of 1928.

[4] Noblesville has won fifteen state championships:[5] In 2020, NHS announced plans to build a new sports complex, replacing one constructed in 1969.

[6] NHS has four competitive show choirs: the mixed-gender "NHS Singers", the all-female "New Dimension" and "Sensation" and the all-male "MaleTonez".

[7] NHS is also known for their award winning Bands, regularly achieving gold rating at ISSMA contests.