Wesley Guy Whisler (born April 7, 1983) is an American former Major League Baseball pitcher who played for the Chicago White Sox in 2009.

He was drafted out of high school in the 41st round by the Chicago Cubs, but opted to play three seasons for the UCLA Bruins.

In 2002 and 2003, he played collegiate summer baseball in the Cape Cod Baseball League for the Yarmouth-Dennis Red Sox, and received the league's Outstanding Pro Prospect award in 2002.

Whisler was granted free agent status at the conclusion of the 2010 baseball season and re-signed with the White Sox on March 8, 2011.

He did not have any Major League appearances for the White Sox, instead playing for the Low A Kannapolis Intimidators, for the High A Winston-Salem Dash, Double A Birmingham Barons and finishing the season with the Charlotte Knights.