The two-lane coastal highway is 15.2-mile-long (24.5 km) and connects Bayboro with communities in northeastern Pamlico County.

Briefly passing through some residential neighborhoods of the town, the highway heads northeast through agricultural lands and woodlands of the eastern side of the county.

[1] At the unincorporated community of Hollyville, NC 307 heads east to serve the town of Vandemere while NC 304 bends to the north and the east to enter the town of Mesic.

The two roads cross the Intracoastal Waterway on a high-level bridge before descending into the census-designated place of Hobucken.

[2] Established in 1923 as a new primary routing, it ran from NC 302, in Bayboro, to end in Vandemere.