It is located on the outskirts of the educational hub hills City of the Northeastern India, Shillong, the "Scotland of the East".

The present full-fledged tertiary care hospital facilities started at its permanent campus at Mawdiangdiang, Shillong in the year 2007.

(1) The MBBS teaching programme of NEIGRIHMS started in 2008 with intake of 50 (fifty) students, followed by Post graduate courses in the following 4 subjects - Anaesthesiology, Microbiology, Obstetrics & Gynaecology and Pathology in the year 2009.

The institute is established on the lines of AIIMS New Delhi and PGIMER Chandigarh, to provide tertiary care to the people of North-East India.

The approval to start the Post Graduate course in NEIGRIHMS was conveyed by the Ministry vide Office Memorandum No-U-12012/7/2008-NE dated 19 May 2008.

Director General, DGHS, the Ministry vide letter No.U-12012/7/2008-NE (Pt) dated 19 March 2009 permitted to start Post Graduate Courses with 2 seats, each in 4 departments namely Anaesthesiology, Pathology, Microbiology and Obstetrics & Gynaecology.

A central library with a vast collection of medical books and journals along with internet connectivity, photocopy and printing facilities are available to everyone in the campus.

50 Students are admitted every year for the undergraduate course of MBBS from 8 north eastern states and from All India quota after qualifying NEET UG.

The best way to reach NEIGRIHMS is from the Police Bazaar through Polo Bazaar- NEEPCO Office - Demseiniong - Nongmynsong - Project Setuk HQ-NEIGRIHMS, Mawdiangdiang.

City buses, Supplementary State Transport (Tata Magic) and cabs(Maruti 800 and Alto) ply at intervals from various places of Shillong to Mawdiangdiang.