The school was originally located at the northwest corner of Dayton Street and East Tallmadge Avenue in what later became Jennings Middle School, a building that stood until 2012.

In 1931 the present North High School was built on Gorge Boulevard and housed students in grades 10–12.

Completion of the building was delayed 24 years because of the depression and two wars.

In 1955 an auditorium, cafeteria, and gymnasium were added, followed by a vocational wing in 1970.

The tilework features theme of brightly colored neighbors, stylized flowers, and images of pre-industrial humans depicted in industrious scenes.