The newly established North Quincy High School graduated its first class of seniors in 1934, and a second wing was added to the building two years later.

A large new wing in the Brutalist style was added to the rear of the building, designed by the Colletti Brothers of Hingham,[3] built atop Oliver Street, which was controversially razed for the construction; the old glass "gondola" in the rear of the old building which served as the principal's office in the 1950s and 1960s was also removed.

[4] Finally, the entrance to the school was changed, removing stairs leading into a second-floor vestibule as well as two flanking concrete statues of lions.

The school is once again slated to undergo exterior renovations, beginning with the purchase and razing of much of Hunt Street, and nine houses occupying the section, which will be replaced with parking and access to nearby Teal Field, as well as the fencing in of the entire campus, in conjunction with ongoing modifications of Hancock and West Squantum Streets for easing of traffic constrictions.

The Atrium honors North Quincy High School students and graduates who have served in the U.S. military.

Wall panels are dedicated to Pope, Caddy, E. Alan Brudno, Richard A. Stratton, and Charles Sweeney.

[1] "North" competed for many years in the high school Atlantic Coast and Old Colony Leagues, which comprised teams from the South Shore.

[7] MOON (Mathematical Organization of North Quincy) has competed in the Greater Boston Math League.

The Model United Nations club participates in academic discussions and intellectual forums throughout the Boston area.

The Quizbowl team participates at various tournaments, notably winning WGBH’s High School Quiz Show in 2013 and in 2022.

[7] As of 2013, persons of Asian origin make up 92% of the cadets in the North Quincy High JROTC program.

The Drama Club has put on many plays, including Flowers for Algernon, Leading Ladies, and Brighton Beach Memoirs.

The Hip Hop Club is a team of students who practice various dance forms, such as bboying, pop and lock, and freestyle.

Mr. Yakoo, the school mascot, is a caricature of Armenian American dentist and NQHS benefactor Alan Yacubian, which was the subject of controversy for its longstanding use of Indian warrior dress.

[12] In 2017, Mayor Thomas P. Koch called Yakoo a symbol of pride and said the issue shouldn't be dictated by "social justice zealots out there who know what’s best for everybody.

A petition collected several thousand signatures and led to an open letter from a group of North Quincy students to administrators alleging racially hostile behavior at the school.

[14] In an effort to preserve the legacy of the Yakoo while modernizing it, original illustrator Peter Fredericksen redrew the mascot with the creative input of Yacubian.

A revision of the mascot was unveiled in August 2020, retaining the caricature of Yacubian as originally drawn, but donning the outfit of a patriot of the Revolutionary War era, with a scroll in hand in lieu of a rock, tripoint hat in place of a Mohawk, and the removal of the arrowhead and feathers.

One program is between North Quincy High School Italian students and the Prima Maggiore Vittoria Collona Liceo Linguistico located in Arezzo, Italy.