The Homebush to Hornsby section of the Main North railway line was first opened in 1886, and a connection from the Main North railway line to Strathfield to the east was subsequently added.

North Strathfield station was added to the line much later: it opened on 9 June 1918 as an island platform with two faces.

This connection is mainly used by freight trains but is occasionally used by passenger trains travelling to Olympic Park station during trackwork or for major events at Sydney Olympic Park.

[5][6][7][8] As part of the Sydney Metro West project, a further two platforms will be built.

[9][10][11] As part of the accesbility projects, the station was upgraded and given lifts in November 2019.