Northwest Italy (Italian: Italia nord-occidentale or just Nord-ovest) is one of the five official statistical regions of Italy used by the National Institute of Statistics (ISTAT), a first level NUTS region and a European Parliament constituency.

Northwest encompasses four of the country's 20 regions: It borders to the west with France via the Western Alps, to the north with Switzerland via the Central Alps, to the east with the regions of Trentino-Alto Adige, Veneto and Emilia-Romagna belonging to Northeast Italy and to the south with the Ligurian Sea and the extreme offshoot of Tuscany in Central Italy.

In 2022, the population resident in north-western Italy amounts to 15,817,057 inhabitants.

[1] Below is the list of the population residing in 2022 in municipalities with more than 50,000 inhabitants:[1] The gross domestic product (GDP) of the region was 580.3 billion euro in 2018, accounting for 32.9% of Italy's economic output.

GDP per capita adjusted for purchasing power was 35,900 euro or 119% of the EU27 average in the same year.