Notre Dame Junior Senior High School (NDJSHS) is a co-ed Catholic high school in Utica, New York.

It is part of the Roman Catholic Diocese of Syracuse.

The land that the school was built on was the former location of a military hospital.

Initially, the school owned the land currently occupied by the Utica Business Park, but sold most of it to the city, creating its current boundaries.

[1] The school hosts a Navy Junior Reserve Officers Training Corps Unit.