In late 2000 Nuala began playing alongside Kris Drever and Anna-Wendy Stevenson in a weekly Friday session at Sandy Bell's pub in Edinburgh.

The trio became known as Fine Friday and toured in the UK, Europe and Australia, releasing two albums before disbanding.

[2] She has collaborated, performed and recorded with Will Oldham,[3] Norman Blake from Teenage Fanclub,[4] Cathal McConnell from Boys of the Lough,[5] Frode Haltli, Vegar Vardal, Oliver Schroer,[6] John Doyle,[7] and American singer-songwriter, AJ Roach[8] Nuala tours globally as Nuala Kennedy Band headlining at major festivals such as Rudolstadt (GER) Telemark (NOR) Celtic Connections (UK) Celtic Colours International (CAN) Festival Interceltique de Lorient (FRA) Eurofonik (FRA) and Milwaukee Irish Festival (US).

She is a member of Oirialla playing music from her native Oriel alongside Gerry O'Connor, accordionist Martin Quinn and Breton guitarist Gilles Le Bigot.

Nuala also plays in the Irish traditional music power trio, The Alt, with John Doyle and Eamon O'Leary.