Nymphaea potamophila is a species of waterlily native to the region spanning from Venezuela to northern Brazil.

The abaxial surface has a greenish base colour accompanied by dark red variegation, but also exhibits patterns of branched, rusty-brown striations.

[4] The nocturnal floating flowers are connected to glabrous, 4 mm wide peduncles, which can exceed 4 m in length.

[5][7] High levels of both pollen viability and seed production are evident in Nymphaea potamophila.

[4][7] It can be found in the aquatic habitats of the Amazon Rainforest,[5] where it can grow along river margins in up to 4-5 m deep water.