2359550793ENSG00000135336ENSMUSG00000040044Q9UBD5Q9JK30NM_001197259NM_012381NM_181837NM_001159563NM_015824NP_001184188NP_036513NP_862820NP_001153035NP_056639Origin recognition complex subunit 3 is a protein that in humans is encoded by the ORC3 (ORC3L) gene.
Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.
Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory.
Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
[7] ORC3 has been shown to interact with: This article on a gene on human chromosome 6 is a stub.