OR 212 begins at Interstate 205 and OR 213 in Clackamas and heads east as a four lane highway.

The highway then condenses down to two lanes and continues east heading toward Damascus.

Along the way, there are numerous intersections with backroads that lead to Gresham, Portland's biggest eastern suburb.

It then enters the town of Boring, remaining as a two lane road and reaches its eastern terminus at an interchange with US 26, northwest of Sandy.

A previous alignment through Boring ran due west onto Fireman Way, curving south onto 272nd.