Oregon Route 224 is a state highway which runs through some of Portland's southeastern suburbs and ends in the Cascades.

On the eastern edge of Estacada, OR 224 separates from OR 211, and heads southeast into the Mount Hood National Forest, here you are in the mountains heading to the small community of Ripplebrook, its southeastern terminus, where state highway maintenance ends.

USFS Road 46 was formerly signed as a portion of OR 224,[citation needed] but was never a state-maintained highway.

In those days, Oregon Route 223 followed today's Airlie Rd and Maple Grove Rd between Falls City and Pedee).

[1] The easternmost 19 miles (31 km) of OR 224 in Mount Hood National Forest was closed to traffic during the 2020 Labor Day wildfires, which damaged pavement, guardrails, and nearby trees.

It is the newest highway constructed in the Portland metropolitan area since OR 213 bypassed Oregon City in 1989.