200931106407ENSG00000163959ENSMUSG00000035699Q86UW1Q8R000NM_152672NM_145932NP_689885NP_666044Organic solute transporter alpha, also known as OST-alpha, is a protein which in humans is encoded by the SLC51A gene.

[5][6] OST-alpha together with OST-beta is able to transport estrone sulfate, taurocholate, digoxin, and prostaglandin E2 across cell membranes.

[6][7] The Ost-alpha / Ost-beta heterodimer, but not the individual subunits, stimulates sodium-independent bile acid uptake.

[7] The heterodimer furthermore is essential for intestinal bile acid transport.

[8] OST-alpha and OST-alpha have high expression in the testis, colon, liver, small intestine, kidney, ovary, and adrenal gland.